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Brand name: Ativan

Generic name: Lorazepam

Ativan is used to treat anxiety. Ativan belongs to a class of drugs known as benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. Ativan works by enhancing the effects of a certain natural chemical in the body (GABA).

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How To Use Ativan

Take Ativan by mouth with or without food as directed by your doctor. Dosage is based on your medical condition and response to therapy.

If directed by your doctor, use Ativan regularly in order to get the most benefit from it. To help you remember, use it at the same time(s) each day.

Ativan may cause dependence, especially if it has been used regularly for an extended time (more than 1-4 weeks), if it has been used in high doses, or if you have a history of alcoholism, drug abuse, or personality disorder. In such cases, if you suddenly stop Ativan, withdrawal reactions may occur.

Such reactions can include seizures, trouble sleeping, mental/mood changes, increased reactions to noise/touch/light, nausea, vomiting, diarrhea, loss of appetite, stomach pain, hallucinations, numbness/tingling of arms and legs, muscle pain, fast heartbeat, short-term memory loss, and very high fever.

Report any such reactions to your doctor immediately. When stopping extended, regular treatment with Ativan, gradually reducing the dosage as directed will help prevent withdrawal reactions. Consult your doctor or pharmacist for more details.

Though it is very unlikely to occur, Ativan can also result in abnormal drug-seeking behavior (addiction/habit forming). Do not increase your dose, take it more frequently, or use it for a longer time than prescribed. Properly stop Ativan when so directed. This will lessen the chances of becoming addicted.

Do not suddenly stop using Ativan without your doctor's approval. Some conditions may become worse when Ativan is abruptly stopped. Your dose may need to be gradually decreased.

When used for an extended time, Ativan may not work as well and may require different dosing. Talk with your doctor if Ativan stops working well. Do not increase your dose without first talking to your doctor.

Inform your doctor if your condition persists or worsens.

Overdose with Ativan

If an overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include confusion, slow reflexes, clumsiness, deep sleep, and loss of consciousness.

Missed Dose of Ativan

If you miss a dose and are taking more than 1 dose daily, do not take it if it is almost time for the next dose. Instead, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. If you take it once daily at bedtime and miss a dose, do not take it the following morning. Call your doctor to find out what to do.

Ativan Notes

Lifestyle changes such as starting a stress reduction program may increase the effectiveness of this medicine. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.

Do not share Ativan with others.

Laboratory and/or medical tests (e.g., blood counts, liver function tests) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

Ativan Storage

Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Properly discard the Ativan when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your Ativan.

Side effects with Ativan

Drowsiness, dizziness, loss of coordination, headache, nausea, blurred vision, change in sexual interest/ability, hair loss, constipation, heartburn, or change in appetite may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed Ativan because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Ativan do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

memory loss
shaking
difficult/slurred speech
vision changes
mental/mood changes (e.g., depression, including rare thoughts of suicide)
trouble breathing (especially during sleep)
stomach/abdominal pain
yellowing of skin/eyes
dark urine
seizures
easy bruising/bleeding
signs of infection (e.g., fever, persistent sore throat)
unusual weakness
low body temperature

A very serious allergic reaction to Ativan is unlikely, but seek immediate medical attention if it occurs.

Symptoms of a serious allergic reaction may include:

rash
itching
swelling
severe dizziness
trouble breathing

This is not a complete list of possible side effects when taking Ativan. If you notice other effects not listed above, contact your doctor or pharmacist.

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

Ativan should not be used with the following medication because a very serious interactions may occur:

sodium oxybate (also known as gamma hydroxybutyrate or GHB)

If you are currently using this medication listed above, tell your doctor or pharmacist before starting Ativan.

Before using Ativan, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

aminophylline
clozapine
kava
probenecid
theophylline
valproate

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone).

Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.

This page on Ativan does not contain all possible interactions. Therefore, before using Ativan, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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