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Generic name: Alendronate Sodium
Brand name: Fosamax
Why is Fosamax prescribed ?
Fosamax is prescribed for the prevention and treatment of
osteoporosis, the brittle bone disease, in postmenopausal
women. It is also used to increase bone mass in men with osteoporosis,
and is prescribed for both men and women who have developed
a form of osteoporosis sometimes caused by steroid medications
such as prednisone. This drug can also be used to relieve
Paget's disease of bone, a painful condition that weakens
and deforms the bones.
Most important fact about Fosamax
For Fosamax to be effective, you must take the tablets without
food or other medications, exactly as directed.
How should you use Fosamax ?
Fosamax is effective only when each tablet is taken with
a full glass of plain water first thing in the morning, at
least 30 minutes before the first food, beverage, or other
medication. If you can wait longer before eating or drinking,
Fosamax will be absorbed better. Do not lie down for at least
30 minutes after taking Fosamax and avoid chewing or sucking
on the tablet; it can cause mouth sores.
You should take calcium and vitamin D supplements if you
don't get enough in your diet. Avoid smoking and alcohol.
Weight-bearing exercise can also strengthen bones.
If you miss a dose of Fosamax
If you are taking Fosamax on a daily basis, do not take a
missed dose later in the day, Instead, skip it and go back
to your regular schedule the next morning.
If you are taking Fosamax once a week, take 1 tablet the
morning after you remember, then return to your original once-weekly
schedule on the chosen day. Do not take 2 tablets on the same
day.
Storage instructions for Fosamax
Keep the container tightly closed and store at room temperature.
What side effects when taking Fosamax may occur ?
Side effects cannot be anticipated. If any develop or change
in intensity, inform your doctor as soon as possible. Only
your doctor can determine if it is safe for you to continue
using Fosamax.
More common side effects when taking Fosamax may include:
Abdominal pain, bone and joint pain, constipation, diarrhea,
indigestion, muscle pain, nausea
Less common side effects when taking Fosamax may include:
Abdominal distention, acid backup, difficulty in swallowing,
esophageal ulcers, gas, headache, stomach ulcers, vomiting
Rare side effects when taking Fosamax may include:
Changes in taste, esophageal blockage or perforation, eye
pain, hives, inflammation of the stomach, mouth sores, muscle
cramps, rash, skin redness, swollen face and throat
Why should Fosamax not be prescribed ?
You should not take Fosamax if the calcium level in your
blood is low. Avoid Fosamax if it causes an allergic reaction.
Special warnings about Fosamax
Fosamax is not recommended for women on hormone replacement
therapy, or for women with kidney problems.
Be sure to tell your doctor if you have trouble swallowing
or have any digestive disease. Fosamax may cause problems
in your esophagus such as inflammation, ulcers, bleeding,
and in rare cases, blockage or perforation.
Possible food and drug interactions when taking Fosamax:
Combining aspirin with a Fosamax dose of more than 10 milligrams
per day will increase the likelihood of stomach upset.
Calcium supplements such as Caltrate, antacids such as Riopan,
and some other oral medications will interfere with the absorption
of Fosamax, so wait at least 30 minutes after taking Fosamax
before you take anything else.
Special information if you are pregnant or breastfeeding
The effects of Fosamax during pregnancy and breastfeeding
have not been adequately studied. If you are pregnant or plan
to become pregnant, notify your doctor immediately. It is
not known whether Fosamax appears in breast milk. Fosamax
is not recommended for nursing mothers.
Recommended dosages for Fosamax
POSTMENOPAUSAL OSTEOPOROSIS
The usual dose of Fosamax is one 10-milligram tablet once
a day or one 70-milligram tablet once a week. Treatment continues
for years.
PREVENTION OF POSTMENOPAUSAL OSTEOPOROSIS
The usual dose is one 5-milligram tablet once a day or one
35-milligram tablet once a week.
OSTEOPOROSIS IN MEN
The usual dose is one 10-milligram tablet once a day or one
70-milligram tablet once a week.
STEROID-INDUCED OSTEOPOROSIS
The usual dose is one 5-milligram tablet once a day, except
for postmenopausal women not taking estrogen, who should take
one 10-milligram tablet once daily.
PAGET'S DISEASE
The usual dose is 40 milligrams once a day for 6 months.
Overdosage with Fosamax
Any medication taken in excess can have serious consequences.
If you suspect an overdose of Fosamax, seek medical attention
immediately.
Symptoms of Fosamax overdose may include:
Heartburn, inflammation of the esophagus or stomach, ulcer,
upset stomach
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